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The Effects of Patient and Visit Characteristics on Health Outcomes in Knee Osteoarthritis

NCT06574191 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 220

Last updated 2026-03-30

No results posted yet for this study

Summary

The goal of this clinical trial is to understand the patient and clinic visit characteristics that affect health outcomes for individuals with knee osteoarthritis (OA) pain using topical diclofenac gel. The main questions it aims to answer are:

* What baseline patient characteristics predict response to topical diclofenac?
* Does patient physiology during the study visit predict response to topical diclofenac?
* Do study visit characteristics predict response to topical diclofenac?

Participants will:

* attend 2 study visits to complete study questionnaires and have blood drawn
* apply topical diclofenac to their knee for 8 weeks
* complete biweekly questions about knee pain and diclofenac use between study visits

Conditions

Interventions

DRUG

Topical Diclofenac gel 1%

Topical NSAID

Sponsors & Collaborators

Principal Investigators

  • Michelle Dossett, MD, PhD · University of California, Davis

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-29
Primary Completion
2028-01-27
Completion
2028-01-27

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06574191 on ClinicalTrials.gov