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Effect of Remazolam on Hemodynamics During Hepatectomy

NCT06565715 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2025-03-18

No results posted yet for this study

Summary

There is high incidence of hemodynamic instability in patients undergoing hepatectomy with low central venous pressure, especially in general anesthesia combined with epidural anesthesia. Remazolam, a new benzodiazepine, has no significant cardiovascular inhibitory effect. Investigators hypothesis that remazolam will provide better hemodynamic when compared with propofol in patients undergoing hepatectomy with general anesthesia combined with epidural anesthesia.

Conditions

  • Hemodynamic Instability

Interventions

DRUG

Remimazolam

Remimazolam is used for sedation during anesthetic induction and maintenance.

DRUG

Propofol

propofol is used for sedation during anesthetic induction and maintenance.

Sponsors & Collaborators

  • Jun Zhang

    lead OTHER

Principal Investigators

  • Jun Zhang, Professor · Fudan University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-08-23
Primary Completion
2024-10-30
Completion
2024-11-08

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06565715 on ClinicalTrials.gov