Effect of Remimazolam on Postoperative Delirium
NCT06180876 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 264
Last updated 2026-02-23
Summary
Remimazolam is a novel benzodiazepine with ultra-short onset and offset of its effect. It can be used for general anesthesia. However, classical benzodiazepine such as midazolam was reported to increase the risk of postoperative delirium. Thus, the investigators aim to investigate the effect of remimazolam general anesthesia on postoperative delirium in elderly patients.
Conditions
- General Anesthetic Drug Adverse Reaction
Interventions
- DRUG
-
remimazolam
continuous infusion
- DRUG
-
propofol
continuous infusion
Sponsors & Collaborators
-
Zhihong LU
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-07-25
- Primary Completion
- 2024-01-25
- Completion
- 2024-01-30
Countries
- China
Study Locations
More Related Trials
-
Remimazolam and Propofol Anesthesia in Elderly Patients
NCT05201300 ·Status: COMPLETED ·Phase: NA
-
Remifentanil and Midazolam on Propofol for Loss of Consciousness in Elderly Patients
NCT02818387 ·Status: UNKNOWN ·Phase: NA
-
Comparison of Postoperative Delirium in Elders Anaesthetised With Midazolam and Without Midazolam
NCT05456230 ·Status: COMPLETED
-
Postoperative Quality of Recovery After General Anesthesia With Remimazolam
NCT06332157 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery
NCT07113483 ·Status: RECRUITING ·Phase: PHASE3
-
Impact of Remimazolam on Prognosis After Bladder Cancer Surgery
NCT04532606 ·Status: RECRUITING ·Phase: PHASE4
-
Remimazolam vs. Propofol: Impact on Postoperative Delirium in Neurosurgical Patients
NCT06115031 ·Status: RECRUITING ·Phase: NA
-
Remimazolam and Endovascular Procedures of Cerebrovascular Diseases
NCT04950621 ·Status: COMPLETED ·Phase: NA
-
Median Effective Dose of Remimazolam for Sedation in Elderly Patients
NCT05468996 ·Status: COMPLETED ·Phase: PHASE4
-
Differential Effects of Remimazolam and Propofol on Dynamic Cerebral Autoregulation During General Anesthesia
NCT05533580 ·Status: UNKNOWN ·Phase: NA
-
Remimazolam Besylate in Sedation of Postcardioperative Patients
NCT06716840 ·Status: RECRUITING ·Phase: NA
-
The Effect of Remimazolam on Postoperative Sleep Quality
NCT07094945 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Explore the Advantages of Remimazolam Used on Gastroscopy
NCT05429086 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Remazolam on Hemodynamics During Hepatectomy
NCT06565715 ·Status: COMPLETED ·Phase: PHASE4
-
The Impact of Remimazolam Tosilate on Oxygenation and Postoperative Cognitive Function in Elderly Patients Undergoing Thoracoscopic Lobectomy
NCT07086911 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Study of the Efficacy and Safety of Remimazolam in General Anesthesia in Adults Undergoing Cardiac Surgery
NCT02523859 ·Status: TERMINATED ·Phase: PHASE3
-
Clinical Studies of the Efficacy and Safety of Remimazolam for Anesthesia Induction and Maintenance in Elderly Patients
NCT06690424 ·Status: COMPLETED ·Phase: PHASE4
-
The Effects of Remimazolam on Cerebral Blood Flow Following General Anesthesia Induction
NCT07303985 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Remimazolam and Propofol on Postoperative Delirium
NCT05514405 ·Status: RECRUITING ·Phase: NA
-
REmimazolam vs PrOpofol on Intraoperative hypotenSion in Major Noncardiac surgEry
NCT05436522 ·Status: COMPLETED ·Phase: PHASE4
-
Remimazolam Phase II Cardiac Anesthesia Study
NCT01937767 ·Status: COMPLETED ·Phase: PHASE2
-
Remimazolam for Cataract Surgery
NCT05980117 ·Status: RECRUITING ·Phase: PHASE4
-
Sevoflurane and Propofol Anesthesia on Postoperative Delirium
NCT01995214 ·Status: UNKNOWN ·Phase: PHASE4
-
Network Pharmacology Was Applied to Explore the Mechanism of Remimazolam Applied in General Anesthesia for Gynecological Surgeries
NCT06990763 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Remifentanil and Midazolam on Propofol for Loss of Consciousness
NCT02536690 ·Status: COMPLETED ·Phase: NA