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Relationship Between Serum β2-Microglobulin and Infiltration of CD8+ in the Tumor Tissue of Hodgkin's Lymphoma Patients

NCT06564259 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 144

Last updated 2024-08-21

No results posted yet for this study

Summary

In newly diagnosed Hodgkin lymphoma patients, pre-treatment Beta-2 Microglobulin (B2M) levels will be measured. A thorough baseline assessment will be performed using CT imaging, and tumor tissue samples will be collected for Immunohistochemical (IHC) analysis to quantify CD8+ cell infiltration. Patients will be closely monitored throughout their treatment, with a follow-up CT scan at the end of therapy to evaluate therapeutic response. This study aims to investigate the correlation between pre-treatment B2M levels and CD8+ immune cell infiltration in tumor tissues, assessing their potential as predictive markers for chemotherapy response.

Conditions

Sponsors & Collaborators

  • Tishreen University

    lead OTHER

Principal Investigators

  • Firas Hussien, Prof. · Tishreen University

  • Maram Bilal, Prof. · Tishreen University

  • Hasan Khalil, Ms · Tishreen University

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-04
Primary Completion
2024-08-15
Completion
2024-08-15

Countries

  • Syria

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06564259 on ClinicalTrials.gov