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Ventilator Settings for Bronchoscopy During Mechanical Ventilation: a Randomized Controlled Study

NCT06562725 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 46

Last updated 2025-07-08

No results posted yet for this study

Summary

Fiberoptic bronchoscopy (FOB) can cause a significant increase in respiratory resistances and airway pressure during mechanical ventilation (MV), which can jeopardize the delivery of the ventilatory assistance. This randomized controlled study tests the hypothesis that new ventilator settings aimed at reducing airway pressure may facilitate FOB during MV. Results of this trial should lead to propose a new ventilatory strategy for critically ill patients needing a FOB procedure under MV.

Conditions

  • Mechanical Ventilation Complication
  • Fiberoptic Bronchoscopy
  • Critical Illness
  • Acute Respiratory Failure

Interventions

OTHER

specific ventilator settings

The special ventilator settings used in the intervention group - aimed at reducing airway pressure - include inspiratory flow \<25 L/min, tidal volume = 5m L/Kg, inspiratory time = 1 sec, respiratory frequency \<20 c/min, PEEP = 5 cmH2O, and FiO2 = 100%

Sponsors & Collaborators

  • Centre Hospitalier Arras

    lead OTHER

Principal Investigators

  • Malcolm LEMYZE, Dr · arras hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-09-10
Primary Completion
2025-06-12
Completion
2025-06-19

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06562725 on ClinicalTrials.gov