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Multifocal HD-tDCS and Motor Function

NCT06561165 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-02-17

No results posted yet for this study

Summary

The purpose of this study is to understand how the brain controls movement and how Non-invasive Brain Stimulation (NIBS) with a technique called High-density transcranial direct current stimulation (HD-tDCS) can alter brain processes to improve behavior. Participants in this study will be randomized to either HD-tDCS with standard intervention or personalized dose-controlled multifocal network-targeted HD-tDCS.

The hypothesis is that dexterous hand function will improve after a standard HD-tDCS dose and increase even more after personalized dose-controlled multifocal network-targeted HD-tDCS.

Conditions

  • Healthy

Interventions

DEVICE

Standard HD-tDCS intervention

Participants will have three sessions along with behavioral assessments.

DEVICE

Multifocal network targeted HD-tDCS intervention

Participants will have three sessions along with behavioral assessments.

DEVICE

Functional Magnetic Resonance Imaging (fMRI)

Participants will have an MRI before or after having HD-tDCS intervention.

Sponsors & Collaborators

  • Medical University of South Carolina

    collaborator OTHER

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    collaborator NIH

  • University of Michigan

    lead OTHER

Principal Investigators

  • Michael Vesia, PhD · University of Michigan

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-02-25
Primary Completion
2027-01-25
Completion
2027-01-25
FDA Device
Yes

Countries

  • United States

Study Locations

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Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06561165 on ClinicalTrials.gov