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Surgical and Pharmacological Efficacy of Knosp Grade 0-2 Prolactinoma

NCT06556186 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 600

Last updated 2024-08-15

No results posted yet for this study

Summary

The investigators carried out a multi-center comparative study, involving hospitals including the Second Affiliated Hospital of Zhejiang University School of Medicine, Peking Union Medical College Hospital, West China Hospital, Wenzhou First Hospital, and Li Huili Hospital. This study aimed to compare the efficacy of medication and surgery for specific subtypes of microadenomas and clearly defined macroadenomas (Knosp grades 0-2), in order to determine which is more effective and which has fewer benefits, thereby enhancing the evidence base.

Conditions

  • Pituitary Tumor

Interventions

PROCEDURE

Transnasal transsphenoidal pituitary lesion resection under neuroendoscopy

Transnasal transsphenoidal pituitary lesion resection under neuroendoscopy

DRUG

Bromocriptin 2.5mg, 2-3 times a day

Bromocriptin 2.5mg, 2-3 times a day

Sponsors & Collaborators

  • Peking Union Medical College Hospital

    collaborator OTHER

  • West China Hospital

    collaborator OTHER

  • First Affiliated Hospital of Wenzhou Medical University

    collaborator OTHER

  • Ningbo Medical Center Lihuili Hospital

    collaborator OTHER_GOV

  • Second Affiliated Hospital, School of Medicine, Zhejiang University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-01
Primary Completion
2027-03-31
Completion
2027-03-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06556186 on ClinicalTrials.gov