Clinical Characteristics and Prognosis of Acute Stroke in Pregnancy and Puerperium

Summary

The objectives of this study are: (1) to describe the detailed clinical characteristics and prognosis of ASPP patients in order to explore the risk factors of ASPP, and to compare the short-term and long-term functional recovery outcomes between them and their controls; (2) to evaluate the risk of recurrent stroke, particularly during subsequent pregnancies, in ASPP patients; (3) to assess the short-term and long-term outcomes of their offsprings and their future development status.

This study is divided into three parts. The first part is a case-control study to explore the risk factors of ASPP and the predictors of the prognosis of ASPP patients. The second part is a cohort study to evaluate the impact of ASPP on the risk of recurrent stroke. The third part is a cohort study to assess the impact of ASPP on the short-term and long-term outcomes of their offsprings by comparing the offsprings of ASPP patients with the offsprings of non-ASPP participants.

Conditions

• Pregnancy-associated or Puerperium-associated Acute Stroke

Sponsors & Collaborators

• Affiliated Hospital of Jiangnan University

  collaborator OTHER

• Affiliated Hospital of Nantong University

  collaborator OTHER

• Baotou Central Hospital

  collaborator OTHER

• First Affiliated Hospital of Harbin Medical University

  collaborator OTHER

• First Affiliated Hospital Xi'an Jiaotong University

  collaborator OTHER

• Jiangyin People's Hospital

  collaborator OTHER

• Qianfoshan Hospital

  collaborator OTHER

• RenJi Hospital

  collaborator OTHER

• Second Affiliated Hospital of Soochow University

  collaborator OTHER

• Second Hospital of Shanxi Medical University

  collaborator OTHER

• Shanxi Bethune Hospital

  collaborator OTHER

• Shenzhen Second People's Hospital

  collaborator OTHER

• The Affiliated Hospital of Qingdao University

  collaborator OTHER

• The First Affiliated Hospital of Nanchang University

  collaborator OTHER

• The First Affiliated Hospital of University of Science and Technology of China

  collaborator OTHER

• The First Affiliated Hospital of Zhengzhou University

  collaborator OTHER

• The Second Affiliated Hospital of Hainan Medical University

  collaborator OTHER

• Lanzhou University Second Hospital

  collaborator OTHER

• Tianjin Huanhu Hospital

  collaborator OTHER

• Tianjin Medical University General Hospital

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• Xiangya Hospital of Central South University

  collaborator OTHER

• Xinxiang Central Hospital

  collaborator OTHER

• Zhejiang Provincial People's Hospital

  collaborator OTHER

• Binzhou Medical University

  collaborator OTHER

• Chongqing Medical University

  collaborator OTHER

• Tibetan Second People's Hospital

  collaborator UNKNOWN

• Beijing Tiantan Hospital

  lead OTHER

Principal Investigators

• Xingju Liu, MD · Beijing Tiantan Hospital

• Jizong Zhao, MD · Beijing Tiantan Hospital

Eligibility

Sex

FEMALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-07-31

Primary Completion

2024-10-31

Completion

2025-06-30

Countries

• China

Study Locations