Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder
NCT06518785 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2025-09-04
Summary
This study aims to examine the effects of Low-Intensity Focused Ultrasound (LIFU) on brain activity in patients with alcohol use disorder.
Conditions
Interventions
- DEVICE
-
Low Intensity Focused Ultrasound
An inhibitory LIFU protocol that allows suppression of neuronal activity in the basal ganglia and thalamus will be used.
Sponsors & Collaborators
-
University of California, San Francisco
lead OTHER
Principal Investigators
-
Khaled Moussawi, MD, PhD · University of California, San Francisco
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-01-07
- Primary Completion
- 2030-09-30
- Completion
- 2030-09-30
- FDA Device
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Cortical rTMS as a Tool to Change Brain Reactivity to Alcohol Cues
NCT02939313 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Cerebellar Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Alcohol Use Disorder
NCT03829761 ·Status: COMPLETED ·Phase: NA
-
Neurofeedback Training of Metacognition in Subjects With Alcohol Use Disorder. Disorder Induces Neural Modifications: an Event-related Potentials Study
NCT05913518 ·Status: RECRUITING ·Phase: NA
-
Influence of TMS on Attention Modulation
NCT05611502 ·Status: RECRUITING ·Phase: NA
-
Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users
NCT04154111 ·Status: COMPLETED ·Phase: NA
-
Clinical Intervention in Alcohol Use Disorder
NCT02168400 ·Status: COMPLETED ·Phase: NA
-
Deep Repetitive Transcranial Magnetic Stimulation for Alcohol Use Disorder
NCT02691390 ·Status: COMPLETED ·Phase: PHASE1
-
Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder
NCT06415721 ·Status: RECRUITING ·Phase: NA
-
Deep Brain Stimulation for Refractory Alcoholism
NCT01798888 ·Status: WITHDRAWN ·Phase: PHASE1
-
Brain Functional Connectivity in Alcohol Use Disorder
NCT02877849 ·Status: COMPLETED
-
A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder
NCT03535129 ·Status: COMPLETED ·Phase: NA
-
Mitigating the Disinhibiting Effects of Alcohol With Transcranial Magnetic Stimulation
NCT07188376 ·Status: RECRUITING ·Phase: NA
-
A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder
NCT05621538 ·Status: RECRUITING ·Phase: NA
-
Interest of tDCS in Help for Supporting Alcohol Abstinence
NCT03287154 ·Status: COMPLETED ·Phase: NA
-
Mindfulness-Based Relapse Prevention for Alcohol Use Disorders in Remission
NCT02147483 ·Status: COMPLETED ·Phase: NA
-
Multimodal Neuroimaging of Alcohol Cues, Cortisol Response, and Compulsive Motivation
NCT04412824 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder
NCT06710431 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Non-invasive Brain Stimulation of the Prefrontal Cortex in Substance Use Disorders
NCT05471154 ·Status: COMPLETED ·Phase: NA
-
Cognitive Retraining and Brain Stimulation for Alcohol Use
NCT02045108 ·Status: COMPLETED ·Phase: NA
-
A Pilot Study of Non-invasive Brain Stimulation to Boost the Efficacy of Psychotherapy in a Community Sample of People Who Drink Alcohol
NCT04770025 ·Status: RECRUITING ·Phase: PHASE2
-
The Effect of Positive and Negative Emotions on Brain Activity in Alcoholics and Nonalcoholics
NCT00001675 ·Status: COMPLETED
-
Eye Movements Desensitization and Reprocessing Intervention in Preventing Craving in Alcohol Use Disorder
NCT05606900 ·Status: COMPLETED ·Phase: NA
-
Metabolism in the Human Brain Following Consumption of a Keto-ester in Alcohol Use Disorder (AUD) With Proton Magnetic Resonance Spectroscopic Imaging (MRSI)
NCT05937893 ·Status: COMPLETED ·Phase: NA
-
Study of Retinal Function Using Electroretinogram in Regular Alcohol Users
NCT03818971 ·Status: COMPLETED ·Phase: NA
-
N-acetylcysteine Treatment of Alcohol Use Disorder In Veterans With TBI
NCT02791945 ·Status: COMPLETED ·Phase: PHASE2