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Effect of Biologic Therapy on Surgical Outcomes for Perforated Crohn's Patients

NCT06511921 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2025-08-17

No results posted yet for this study

Summary

crohn's disease patients who present by intestinal perforation as the first presentation are hard to deal with. Surgical techniques as anastmosis or diversion stoma and active course of the disease may greatly affect the quality of life. In post-operative period, is the priority to avoid the post operative complications and to improve surgical outcomes or to stop active course of the disease and to induce remission?. So, those patients were classified into two groups. one group received biological therapy early post operative and the other group received it 2 or 3 months later after surgery and the investigators will compare results between the two groups.

Conditions

  • Crohn Disease

Interventions

BIOLOGICAL

early biologic therapy

biologic therapy for perforated Crohn's disease in the early postoperative period

BIOLOGICAL

late biologic therapy

no biologic therapy for perforated Crohn's disease up to 2 to3 months in the post operative period

Sponsors & Collaborators

  • Zagazig University

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-07-09
Primary Completion
2025-07-09
Completion
2025-07-09

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06511921 on ClinicalTrials.gov