MedTrace Logo

Early Bowel Resection for Terminal Ileal Crohn's Disease

NCT06116604 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 496

Last updated 2023-11-03

No results posted yet for this study

Summary

The goal of this multicentre mixed -methods study is to understand the patient and clinician perspective on the ideal timing of an operation for Crohn's disease of the terminal ileum (last part of the small bowel). The main questions it aims to answer are:

* What factors influence patients' and clinicians' preferences with regards to the timing of the first bowel resection for isolated Crohn's disease of the terminal ileum?
* What are patients' and clinicians' views on 'early' bowel resection (as an alternative to medical therapy) in this context?
* What are the facilitators and barriers to implementation of early surgery in practice?

Participants will be patients with Crohn's disease of the terminal ileum and healthcare professionals involved in treating inflammatory bowel disease.

Healthcare professionals have previously been asked to participate in an interview to understand their views on the role of surgery for Crohn's disease of the terminal ileum. They will now be invited to participate in a choice exercise to understand how much weight they attribute to various factors and outcomes when choosing between surgery and medication for Crohn's disease of the terminal ileum.

Patients will be asked to participate in:

1. an interview about their treatment choices
2. a choice exercise to understand how much weight they attribute to various factors and outcomes when choosing between surgery and medication for Crohn's disease of the terminal ileum
3. a survey, for patients with a previous ileocaecal resection, assessing their experience of the operation

Conditions

  • Crohn Disease

Sponsors & Collaborators

  • Sheffield Centre for Health and Related Research

    collaborator UNKNOWN

  • University of Sheffield

    collaborator OTHER

  • Crohn's & Colitis UK

    collaborator UNKNOWN

  • Sheffield Teaching Hospitals NHS Foundation Trust

    lead OTHER

Principal Investigators

  • Steven Brown · Sheffield Teaching Hospitals NHS Foundation Trust

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-07
Primary Completion
2025-03-31
Completion
2025-11-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06116604 on ClinicalTrials.gov