Neural Control of Gait & Navigation in ADRD
NCT06501820 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2025-12-02
Summary
Brain network segregation, or independent functioning, declines with age and is associated with slower walking speed. Here, the investigators will determine the extent to which brain vestibular network segregation can be altered with bilateral vestibular cortical transcranial direct current stimulation (tDCS) in older adults with subjective cognitive decline. Participants will be randomly assigned to an active or sham stimulation condition. They will receive three, 20-minute sessions of tDCS while they are walking and performing cognitive tasks. MRI of the brain will be acquired before and after these three sessions.
Conditions
- Aging
Interventions
- DEVICE
-
Transcranial direct current stimulation
2mA transcranial direct current stimulation, applied bilaterally on the scalp, over the brain vestibular cortex
Sponsors & Collaborators
-
National Institute on Aging (NIA)
collaborator NIH -
University of Florida
lead OTHER
Principal Investigators
-
Rachael Seidler · University of Florida
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Max Age
- 89 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-11-13
- Primary Completion
- 2029-05-01
- Completion
- 2030-05-01
- FDA Device
- Yes
Countries
- United States
Study Locations
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