Autologous Tumor-Infiltrating Lymphocyte (GTE-001 Injection ) for Treatment of Patients With Advanced Lung Adenocarcinoma
NCT06491225 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 2
Last updated 2026-04-23
Summary
This study is a Multiple centers, open design aimed at evaluating the safety,efficacy and Production feasibility of Autologous Tumor-Infiltrating Lymphocyte (GTE-001 injection ) for treatment of patients with Advanced lung adenocarcinoma,And evaluate potential biomarkers related to GTE-001 activity.
Conditions
- Advanced Lung Adenocarcinoma;Adult
Interventions
- BIOLOGICAL
-
GTE001 injection
GTE-001 injection to treat Advanced lung adenocarcinoma
Sponsors & Collaborators
-
Grit Biotechnology
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-07-18
- Primary Completion
- 2024-08-27
- Completion
- 2024-08-27
Countries
- China
Study Locations
More Related Trials
-
Anti-CD30 CAR-T Therapy in Patients With Refractory/Relapsed Lymphocyte Malignancies
NCT04008394 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety and Preliminary Efficacy of Anti-CDH17 CAR-T Cell Therapy in Patients with CDH17-positive Advanced Solid Tumors
NCT06820424 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Clinical Study Evaluating the Safety and Efficacy of GT801 Injection in Adult Patients With Relapsed/Refractory CD19-positive B-cell Hematologic Malignancies and Autoimmune Hemolytic Anemia
NCT07205315 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
CAR-T Technology for Recurrent/Refractory Malignant Hematological and Lymphatic Tumors
NCT06647329 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
CD276 CAR-T for Patients With Advanced CD276+ Solid Tumors
NCT04691713 ·Status: UNKNOWN ·Phase: NA
-
Safety and Efficacy of ThisCART7 in Patients With Refractory or Relapsed T Cell Malignancies
NCT05127135 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of GNC-035 in Relapsed or Refractory Non-Hodgkin 's Lymphoma and Other Hematological Malignancies
NCT06066203 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Intravenous Injection of Oncolytic Virus Injection (RT-01) in Patients With Relapsed or Refractory T-cell Lymphoma
NCT05387226 ·Status: UNKNOWN ·Phase: PHASE1
-
Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD5/CD7-Specific CAR-T Cells
NCT06420076 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133
NCT02541370 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Multi-centers, Open-Label, Phase 2 Study to Evaluate the Efficacy and Safety of Donor-Derived CD7 CAR T Cells in Subjects With Relapsed or Refractory T-cell Leukemia/Lymphoma
NCT04689659 ·Status: COMPLETED ·Phase: PHASE2
-
Autologous Tumor-Infiltrating Lymphocyte (GT307) for Treatment of Patients With Solid Tumours
NCT06453057 ·Status: RECRUITING ·Phase: NA
-
Chimeric Antigen Receptor T-Cell (CAR-T) Cells in Patients With R/R T-LBL
NCT05554575 ·Status: UNKNOWN ·Phase: PHASE1
-
CD70 Targeted CAR-T Cells in CD70 Positive Relapsed/Refractory Lymphoma
NCT05948033 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Phase I Clinical Study of YK1101 Injection for the Treatment of Advanced Solid Tumors
NCT07139067 ·Status: RECRUITING ·Phase: PHASE1
-
CAR-T Therapy in Relapsed or Refractory Haematopoietic and Lymphoid Malignancies
NCT03121625 ·Status: UNKNOWN ·Phase: PHASE1
-
The Application of CAR-T Cell Therapy in Relapsed and Refractory Malignant Hematologic Tumors
NCT06911710 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
CD19 Targeted Universal Chimeric Antigen Receptor T Cells Injection for CD19+ Refractory/Relapsed B-cell Malignancies
NCT05105867 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Clinical Study of Multi-targeted CAR-T Therapy in Patients With Relapsed/Refractory B-Cell Lymphoma
NCT07093086 ·Status: WITHDRAWN ·Phase: PHASE1
-
TAA05 Injection in the Treatment of Adult Patients With FLT3-positive Relapsed/Refractory Acute Myeloid Leukemia
NCT05432401 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Study Evaluating Safety and Efficacy of CAR-T Cells Targeting CD123 in Patients With Acute Myelocytic Leukemia
NCT03796390 ·Status: UNKNOWN ·Phase: PHASE1
-
Anti-TRBC1 CAR-T Cell Therapy in Patients With TRBC1 Positive T Cell Malignancies
NCT04828174 ·Status: SUSPENDED ·Phase: PHASE1
-
Treatment of Relapsed or Refractory t(8; 21) AML With Targeted AML1-ETO Neoantigen Cytotoxic T Cells (CTL)
NCT06499025 ·Status: ENROLLING_BY_INVITATION ·Phase: EARLY_PHASE1
-
Clinical Study of Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of Relapsed/Refractory Non-Hodgkin Lymphoma
NCT05420493 ·Status: RECRUITING ·Phase: PHASE1
-
A Novel CAR-T Combined Expression of IL-15 in the Treatment of Malignant Hematological Tumors
NCT06783816 ·Status: RECRUITING ·Phase: NA