Predicting Peripheral Neuropathy of Paclitaxel for Gastric Cancer
NCT06490159 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2025-07-11
Summary
Although advances in chemotherapy have improved the prognosis of gastric cancer patients, many patients still suffer from adverse events. Therefore, it is necessary to establish personalized treatment by identifying patients at high risk for side effects. Although paclitaxel-based therapy is the standard second-line treatment, peripheral neuropathy is a troublesome adverse event. The purpose of this study is to establish a liquid biopsy assay to predict paclitaxel-induced peripheral neuropathy in gastric cancer patients.
Conditions
- Gastric Cancer
- Chemotherapy-induced Peripheral Neuropathy
- Paclitaxel
- Ramucirumab
Interventions
- DRUG
-
Gastric cancer second-line chemotherapy
Sponsors & Collaborators
-
City of Hope Medical Center
lead OTHER
Principal Investigators
-
Koichi Takiguchi, PhD · City of Hope Medical Center
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-10-01
- Primary Completion
- 2026-06-18
- Completion
- 2026-06-18
Countries
- Japan
Study Locations
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