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Mechanical Ventilation on Hippocampus

NCT06480162 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2024-08-09

No results posted yet for this study

Summary

Ventilator-associated brain injury (VABI) frequently occurs in ICU patients. Although animal studies indicate the hippocampus as a key target of VABI, its relevance in human patients remains uncertain. In this study, the investigators aim to monitor hippocampal EEG activity during the weaning process of patients off mechanical ventilation, and also exploring the coupling between breathing patterns and hippocampal activity.

Conditions

  • Mechanical Ventilation Complication
  • Brain Injuries

Interventions

PROCEDURE

Mechanical ventilation

After replacing the electrode, we'll monitor the EEG activity of the hippocampus and other cortex regions while weaning off mechanical ventilation.

Sponsors & Collaborators

  • Beijing Sanbo Brain Hospital

    lead OTHER

Principal Investigators

  • Zhonghua Shi, PhD,MD · Capital Medical University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-08
Primary Completion
2025-04-01
Completion
2025-06-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06480162 on ClinicalTrials.gov