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Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

NCT06466941 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2026-05-22

No results posted yet for this study

Summary

The goal of this observational study is to learn about how regional anesthesia (numbing medication) affects pain in patients with different psychosocial phenotypes such as different levels of concern about pain, sleep issues, and anxiety, who are having surgery.

The main questions are:

1. Do psychosocial factors such as concerns about pain, sleep, anxiety affect the effectiveness of regional anesthesia?
2. Do psychosocial factors and regional anesthesia affect the amount of opioids used after surgery?
3. Do psychosocial factors and regional anesthesia affect development of chronic postsurgical pain?

Conditions

  • Acute Pain
  • Chronic Post Operative Pain
  • Opioid Use

Interventions

PROCEDURE

regional anesthesia

Patients who underwent surgery and received an epidural or peripheral nerve block

PROCEDURE

no regional anesthesia

Patients who underwent surgery and did not received an epidural or peripheral nerve block

OTHER

acute pain consultation

Patients who underwent surgery and had a perioperative (preop, intraop, or postop) acute pain consultation

OTHER

no acute pain consultation

Patients who underwent surgery and did not have a perioperative (preop, intraop, or postop) acute pain consultation

Sponsors & Collaborators

  • Brigham and Women's Hospital

    lead OTHER

Principal Investigators

  • Robert Edwards, PhD · Brigham and Women's Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-07-03
Primary Completion
2027-12-31
Completion
2028-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06466941 on ClinicalTrials.gov