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Investigating aCute heArt failuRe Decongestion Guided by Lung UltraSonography

NCT06465498 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 222

Last updated 2026-04-01

No results posted yet for this study

Summary

The goal of this clinical trial is to investigate whether a lung ultrasonography (LUS)-guided decongestion strategy in adults hospitalized for acute heart failure (AHF) can improve patient-centered outcomes.

The main questions it aims to answer are:

* Does this strategy shorten the length of stay and reduce early hospital readmissions?
* Does this strategy improve patients' symptoms and quality of life ?

Researchers will compare LUS to physical examination (PE).

Conditions

  • Acute Heart Failure

Interventions

PROCEDURE

LUS decongestive strategy

LUS results are documented in the electronic case report form (eCRF) and converted into a common score ranging from absence of congestion to severe congestion. This generic congestion score will be communicated to the treating physician by the research personnel, along with a proposal to step-up, maintain, or step-down the decongestive therapy.

PROCEDURE

PE decongestive strategy

PE results are documented in the eCRF and converted into a common score ranging from absence of congestion to severe congestion. This generic congestion score will be communicated to the treating physician by the research personnel, along with a proposal to step-up, maintain, or step-down the decongestive therapy.

Sponsors & Collaborators

  • University Hospital, Geneva

    collaborator OTHER

  • Antonio Leidi

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-22
Primary Completion
2027-04-30
Completion
2027-04-30

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06465498 on ClinicalTrials.gov