Influence of Air Quality on the Development and Progression of Premature Coronary Artery Disease

NCT06464042 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 4272

Last updated 2024-06-18

No results posted yet for this study

Summary

The new global guidelines from the World Health Organization on air quality provide evidence of the damage that air pollution inflicts on human health at even lower concentrations than previously thought. Different studies have shown an increase in the incidence of coronary artery disease (CAD) in young people in recent decades. The main objective of this project is to study the impact of environmental pollutants on the premature manifestation of CAD from different epidemiological approaches and their impact on the evolution of these patients with a gender perspective. It is a retrospective analytical case-control study nested in a cohort of patients ≤40 years old with a clinical history of CAD including: ST-segment elevation myocardial infarction, non-ST-segment elevation acute coronary syndrome, unstable angina, stable angina or silent angina according to the international classification of diseases.

Conditions

Sponsors & Collaborators

  • Fundacin Biomedica Galicia Sur

    collaborator OTHER
  • Conselleria de Saúde Pública de Galicia

    collaborator UNKNOWN
  • Conselleria de Medio Ambiente, Territorio e Vivenda de Galicia

    collaborator UNKNOWN
  • pablo Juan-Salvadores

    lead OTHER

Principal Investigators

  • Pablo Juan-Salvadores, Pharma, PhD · Instituto de Investigación Sanitaria Galicia Sur (IIS Galicia Sur)

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-23
Primary Completion
2024-12-31
Completion
2025-07-01

Countries

  • Spain

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06464042 on ClinicalTrials.gov