MedTrace Logo

Heliox on the Work of Breathing in Adult Patients With Lower Airway Stenosis

NCT06457399 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 18

Last updated 2024-06-13

No results posted yet for this study

Summary

Heliox (a mixture of Helium and Oxygen) can reduce the work of breathing in patients with airway stenosis by modifying turbulent flow into laminar flow. The aim of this study was to analyze the effect of Heliox versus conventional oxygen therapy in patients with lower airway stenosis on muscular effort measured by electromyography and diaphragmatic ultrasound, thoracoabdominal synchrony assessed with plethysmographic bands, dyspnea, stridor, oxygen saturation, transcutaneous carbon dioxide value, blood pressure, heart rate and respiratory rate.

Conditions

  • Airway Obstruction

Interventions

DRUG

Heliox

Treatment for 30 minutes with Heliox from a commercial tank (Oxhelⓒ, Air Liquideⓒ) with a fixed mixture of 70% helium and 30% oxygen with non-rebreather mask or reservoir bag at a flow of 12-15 lpm.

DRUG

Oxygen

Treatment for 30 minutes with oxygen at FiO2 of 31% with Venturi mask.

Sponsors & Collaborators

  • Hospital Universitario 12 de Octubre

    lead OTHER

Principal Investigators

  • Marta Corral Blanco, MD · Hospital 12 de Octubre

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-27
Primary Completion
2023-05-31
Completion
2024-11-30

Countries

  • Spain

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06457399 on ClinicalTrials.gov