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Personalized Exercise Treatments for Older Veterans With Motoric Cognitive Risk Syndrome

NCT06451874 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 54

Last updated 2025-08-06

No results posted yet for this study

Summary

This study will begin to evaluate personalized preventative dementia treatments for Veterans at risk for developing dementia. The investigators will target Veterans with Motoric Cognitive Risk syndrome (MCR), which is characterized by slow gait speed and cognitive concerns (e.g., problems with memory or concentrations).

Conditions

  • Motoric Cognitive Risk Syndrome

Interventions

BEHAVIORAL

Functional Power Training (FPT)

Participants will receive twice weekly FPT, a progressive functional-based exercises that target optimizing leg force production and leg velocity.

BEHAVIORAL

Music-Based Digital Therapy (MBDT)

Participants will receive twice weekly MBDT, a technology-driven gait training that is grounded in evidence-based rehabilitation treatment, rhythmic auditory stimulation.

BEHAVIORAL

FPT + MBDT

For non-responders who were randomized to augment treatment, they will receive combined FPT and MBDT treatment.

Sponsors & Collaborators

  • VA Office of Research and Development

    lead FED

Principal Investigators

  • Elisa Ogawa, PhD MS BS · VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
SEQUENTIAL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-01
Primary Completion
2029-05-31
Completion
2029-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06451874 on ClinicalTrials.gov