A Model for Drug Concentration Prediction of Vancomycin
NCT06431412 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 401
Last updated 2024-05-28
Summary
Objective: This study aims to use machine learning methods to establish an optimal model for predicting serum vancomycin trough concentrations in critically ill patients.
Methods: This is a single-center, retrospective study. Data on serum vancomycin concentration in the Critical Care Database of Peking Union Medical College Hospital were screened and extracted to construct a prediction model using machine learning methods. The MIMIC-IV (Medical Information Mart for Intensive Care) database will be further used for external verification of the constructed model.
The study has been approved by the Medical Ethics Committee of Peking Union Medical College Hospital (K24C1161).
Conditions
- Critical Illness
- Infections
- Drug Use
Interventions
- OTHER
-
no intervention
no intervention
Sponsors & Collaborators
-
Peking Union Medical College Hospital
lead OTHER
Principal Investigators
-
Li Weng, MD · Peking Union Medical College Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-03-01
- Primary Completion
- 2024-08-31
- Completion
- 2024-08-31
Countries
- China
Study Locations
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