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A Rapid Triage Test to Improve Risk-stratification of Febrile Children (EChiLiBRiST, Clinical Trial 1, Outpatients)

NCT06422338 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 5212

Last updated 2026-02-17

No results posted yet for this study

Summary

The overall aim of the study is to provide evidence that introducing novel biomarkers evaluation at triaging (first clinical assessment), in combination with IMCI-based guidelines (SoC), is a viable strategy to enhance rapid and accurate identification of febrile children at increased risk of life-threatening infections compared to IMCI-based strategies alone (SoC), and to demonstrate whether this results in enhanced decisions of admission/referral vs discharge, and enhanced overall health outcome of children with acute fever in sub-Saharan Africa.

Conditions

Interventions

OTHER

IMCI-enhanced by suPAR levels (SoC + suPAR POC)

IMCI-guidelines (standard of care) + Point-Of-Care (POC) based on suPAR quantification

Sponsors & Collaborators

  • Barcelona Institute for Global Health

    lead OTHER

Principal Investigators

  • Quique Bassat, Prof · Barcelona Institute for Global Health

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
2 Months
Max Age
60 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-02
Primary Completion
2026-12-01
Completion
2027-03-01

Countries

  • Gabon
  • Mozambique

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06422338 on ClinicalTrials.gov