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Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity

NCT06411197 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2025-10-02

No results posted yet for this study

Summary

This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities. The study aims to:

A) Examine how experimental muscle pain in different types of muscles (ankle plantar-flexion, knee extension, and flexion muscles) affects kinematics, kinetics, and muscle activation

Participants will receive six muscle injections: a) Hypertonic saline (painful condition) and b) Isotonic saline (control condition) in 1) m. gastrocnemius, 2) m. semitendinosus, and 3) m. biceps femoris.

Conditions

  • Pain, Acute

Interventions

OTHER

Hypertonic saline injection

Injection with hypertonic saline (7%)

OTHER

Isotonic saline injection

Injection with isotonic saline (0.9%)

Sponsors & Collaborators

  • Kristian Kjær Petersen

    lead OTHER

Principal Investigators

  • Kristian KS Petersen · Aalborg University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-11-08
Primary Completion
2026-06-01
Completion
2026-12-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06411197 on ClinicalTrials.gov