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Short Term Immobilization of the Lower Limb

NCT05072652 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2022-08-19

No results posted yet for this study

Summary

The purpose of this study is to determine the effects of one week of knee-joint immobilization on muscle size, strength, neuromuscular function, and brain function. In addition, the effects of two different interventions (i.e., neuromuscular electrical stimulation and action observation/mental imagery) throughout immobilization will be determined. Following the immobilization period, participants that have lost strength will be rehabilitated with twice weekly resistance training sessions, and sex-based differences in rehabilitation timelines will be examined.

Conditions

  • Weakness, Muscle
  • Muscle Weakness
  • Muscle Loss
  • Muscle Atrophy
  • Injury, Knee

Interventions

OTHER

Neuromuscular Electrical Stimulation

Participants in this group will perform twice daily neuromuscular electrical stimulation training sessions of the quadriceps muscles (specifically, the vastus lateralis and rectus femoris) or the immobilized left leg.

OTHER

Action Observation + Mental Imagery

Participants in this group will perform daily action observation + mental imagery training via video and audio recordings.

Sponsors & Collaborators

  • University of Central Florida

    lead OTHER

Principal Investigators

  • Matt S Stock, PhD · University of Central Florida

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-10-11
Primary Completion
2022-06-01
Completion
2022-07-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05072652 on ClinicalTrials.gov