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Sulfur vs. Different Regimes of Permethrin for Scabies

NCT06396507 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 250

Last updated 2024-05-02

No results posted yet for this study

Summary

In 2017, the World Health Organization (WHO) labeled scabies as a neglected tropical disease. It is a serious health problem especially in poor developing countries like Syria, where overcrowding, poverty, and war consequences are considered major factors for spreading the disease. Permethrin lotion or cream is the treatment of choice for scabies, and it is applied once a week for two consecutive weeks according to the global guidelines. However, most practitioners in Syria do not adhere to this standard regimen, and a variety of regimens are used instead based mostly on clinical experience. In this study, the investigators are comparing four different regimens of permethrin application and comparing Sulfur to permethrin in terms of efficacy and safety.

Conditions

  • Scabies

Interventions

DRUG

Permethrin Solution

permethrin 5 % solution

DRUG

Sulfur

Sulfur 10%+ vaseline 90 % ointment

Sponsors & Collaborators

  • University of Aleppo

    collaborator OTHER

  • Tishreen University Hospital

    collaborator OTHER

  • Damascus University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
2 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-15
Primary Completion
2022-09-15
Completion
2022-11-12

Countries

  • Syria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06396507 on ClinicalTrials.gov