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Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children and Adults

NCT02407782 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 1092

Last updated 2024-06-17

No results posted yet for this study

Summary

Scabies remains a frequent condition that affects adults and children. The aim of this study is to compare the efficacy and safety of two drug treatments against scabies in children and their close contacts. One group will apply topical permethrin 5% and the other group will receive oral ivermectin.

Both groups will be treated twice, once at inclusion and the second time 10 days later. Both treatment regimens have been used widely and are safe to use.

Conditions

  • Scabies

Interventions

DRUG

Ivermectin

oral ivermectin, 200μg/kg given at baseline and at day 10.

DRUG

Permethrin

topical permethrin 5% cream applied at baseline and at day 10.

Sponsors & Collaborators

  • University Hospital, Bordeaux

    lead OTHER

Principal Investigators

  • Bruneau Giraudeau, Doctor · Centre d'investigation clinique Inserm 1415 CHRU de Tours

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-19
Primary Completion
2021-12-16
Completion
2022-01-18

Countries

  • France
  • Guadeloupe

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02407782 on ClinicalTrials.gov