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Proteomic Analysis of Newly Restored Single Implants

NCT06379022 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2024-04-23

No results posted yet for this study

Summary

In 10 systemically healthy non-smokers, free of periodontitis, one newly restored implant (baseline-T0) and one corresponding tooth were followed over 12 months (T1). All implants were screw-retained, and platform-switched. Oral hygiene was closely monitored during the study. Probing pocket depth (PPD), attachment levels (CAL), bleeding and plaque indices and crevicular fluid were collected from an implant-site (PICF) and a tooth-site (GCF). Total proteomic profiles in PICF and GCF were investigated using label-free quantitative proteomics.

Conditions

  • Peri-Implantitis
  • Peri-implant Mucositis
  • Periodontal Diseases

Interventions

BEHAVIORAL

Plaque control

Subjects are motivated for optimal oral hygiene

Sponsors & Collaborators

Principal Investigators

  • Danae A Apatzidou, Assoc. Professor · Dental School, Aristotle University

  • Danae A Apatzidou, Assoc. Professor · Dental School, Aristotle University

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-12-03
Primary Completion
2019-11-29
Completion
2019-11-29

Countries

  • Greece

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06379022 on ClinicalTrials.gov