MedTrace Logo

Effects of Head and Neck Cooling and Heating on Fatigue in Multiple Sclerosis and Healthy Men

NCT06370403 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2024-04-19

No results posted yet for this study

Summary

Local head and neck cooling strategies can help reduce multiple sclerosis-related fatigue, while heating can exacerbate heat-related fatigue. However, no study has detailed the peripheral and central responses to head and neck cooling (at 18°C) and heating (at 43 ± 1°C next to the scalp and neck skin) during fatiguing isometric exercise in non-challenging ambient temperature in multiple sclerosis and healthy male subjects. In addition, there is a lack of data describing the effects of head and neck cooling/heating and strenuous exercise on blood markers, muscle temperature, motor accuracy, and rate of perceived exertion. The investigators hypothesized that: (i) men with multiple sclerosis would be more affected by central and peripheral fatigue compared to healthy subjects; (ii) local cooling will result in greater central fatigue but will be associated with greater peripheral fatigue, whereas heating will result in greater central and peripheral fatigue in multiple sclerosis men; (iv) local cooling and heating will have a greater effect on the release of stress hormones, rate of perceived exertion and motor accuracy compared to the control condition in both multiple sclerosis and healthy groups.

Conditions

Interventions

OTHER

Cooling of the head and neck

Cooling of the head and neck at 18°C next to the head and neck skin in multiple sclerosis and healthy subjects

OTHER

Heating of the head and neck

Heating of the head and neck at 43 ± 1°C next to the head and neck skin in multiple sclerosis

Sponsors & Collaborators

  • Lithuanian Sports University

    lead OTHER

Principal Investigators

  • Gintarė Daukšaitė · Lithuanian Sports University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-02-04
Primary Completion
2016-03-01
Completion
2017-01-08

Countries

  • Lithuania

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06370403 on ClinicalTrials.gov