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Cooling Induces Motor Facilitation With Sympathetic Activation

NCT05832970 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2023-04-27

No results posted yet for this study

Summary

Cryotherapy has beneficial effects such as motor facilitation, increase isometric force generation, and reduce spasticity.

It is known that the muscle spindle has sympathetic innervation. Muscle spindle sensitivity increase with sympathetic activity. This research has three hypotheses: First, short-term cold application to the skin increases sympathetic activity. Second, there is an increase in muscle spindle sensitivity with increased sympathetic activity. Third, the effect of short-term cold on muscle spindle sensitivity continues until the skin temperature returns to normal. The purpose of this research is to test these hypotheses.

Conditions

  • Cryotherapy Effect

Interventions

OTHER

Brief skin cooling

Brief skin cooling will be applied to the hand using the cold-bath immersion

Sponsors & Collaborators

  • Istanbul Physical Medicine Rehabilitation Training and Research Hospital

    lead OTHER_GOV

Principal Investigators

  • ILHAN KARACAN, MD, Prof · İstanbul Physical Therapy Rehabilitation Training & Research Hosptial

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-03
Primary Completion
2023-04-07
Completion
2023-04-08

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05832970 on ClinicalTrials.gov