Evaluation of TWEAK in Plaque Psoriasis and Psoriatic Arthritis Patients
NCT06370156 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2024-04-17
Summary
Psoriasis vulgaris is associated with significant comorbidity including depression, increased risk of cardiovascular events, diminished quality of life, as well as overall increased mortality.
Moreover, concomitant psoriatic arthritis is present in up to 40% of psoriasis patients or will develop in the future.
To enhance quality of life and potentially lower the risk of concomitant disease in psoriasis patients, effective treatment of this immune-mediated systemic inflammatory disease is required
Conditions
Interventions
- DRUG
-
To suggests the role of TWEAK and the effectiveness of different treatments like adalimumab and methotrexate in managing plaque psoriasis and psoriatic arthritis.
Sponsors & Collaborators
-
Egymedicalpedia
lead INDUSTRY
Eligibility
- Min Age
- 20 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-06-01
- Primary Completion
- 2025-06-01
- Completion
- 2025-06-10
Countries
- Egypt
Study Locations
More Related Trials
-
Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasis
NCT00940862 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT00195676 ·Status: COMPLETED ·Phase: PHASE3
-
Trial on the Effect of Adalimumab on Vascular Inflammation in Patients With Psoriasis
NCT01722214 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Secukinumab 300 mg Combined With a Lifestyle Intervention to Secukinumab Alone for the Treatment of Moderate to Severe Psoriasis Patients With Concomitant Metabolic Syndrome
NCT03440736 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Safety and Efficacy of Adalimumab in Subjects With Chronic Plaque Psoriasis and Nail Psoriasis
NCT02016482 ·Status: COMPLETED ·Phase: PHASE3
-
Prevalence and Incidence of Articular Symptoms and Signs Related to Psoriatic Arthritis in Patients With Psoriasis Severe or Moderate With Adalimumab Treatment
NCT01316224 ·Status: COMPLETED
-
Mechanism of Action Study for Psoriasis
NCT00932113 ·Status: COMPLETED ·Phase: PHASE4
-
A Phase 3 Study in Participants With Moderate to Severe Psoriasis
NCT01474512 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT00237887 ·Status: COMPLETED ·Phase: PHASE3
-
Vascular Inflammation in Psoriasis Trial (The VIP Trial)
NCT01553058 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Ixekizumab in Participants With Active Psoriatic Arthritis
NCT01695239 ·Status: COMPLETED ·Phase: PHASE3
-
Controlled Study of Humira in Subjects With Chronic Plaque Psoriasis of the Hands and/or Feet
NCT00735787 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Safety and Efficacy of Efalizumab in Adult Patients With Plaque Psoriasis Involving the Hands and/or Feet
NCT00312026 ·Status: COMPLETED ·Phase: PHASE4
-
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of AbGn-168 in Psoriasis
NCT00848055 ·Status: COMPLETED ·Phase: PHASE1
-
The Purpose of This Research Study is to Compare the Efficacy and Safety of SCT630 and Adalimumab (HUMIRA®) in Adults With Plaque Psoriasis
NCT03927352 ·Status: UNKNOWN ·Phase: PHASE3
-
Efficacy and Safety of Subcutaneous Secukinumab for Moderate to Severe Chronic Plaque-type Psoriasis for up to 1 Year
NCT01365455 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Compare U0267 Against Vehicle in Subjects With Plaque-type Psoriasis One of Two Phase 3 Studies
NCT00688519 ·Status: COMPLETED ·Phase: PHASE3
-
Multicenter Randomized Double Blind Controlled-study to Assess the Potential of Methotrexate Versus Placebo to Improve and Maintain Response to Anti TNF- Alpha Agents in Adult Patients With Moderate to Severe Psoriasis
NCT02829424 ·Status: TERMINATED ·Phase: PHASE4
-
Evaluation of Cardiovascular Risk Markers in Psoriasis Patients Treated With Secukinumab
NCT02559622 ·Status: COMPLETED ·Phase: PHASE3
-
MAP Study: Methotrexate and Adalimumab in Psoriasis
NCT03217734 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Study to Determine the Efficacy and Safety of 122-0551 in Subjects With Plaque Psoriasis
NCT01700985 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Effectiveness and Impact on Health-related Quality of Life in Peruvian Patients With Psoriasis After 16 Weeks of Adalimumab Therapy
NCT01156532 ·Status: TERMINATED
-
Study to Evaluate Efficacy and Safety of MP1032 in Patients With Chronic Plaque Psoriasis
NCT03706209 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Benefit and Safety of GSK2982772 in Moderate to Severe Psoriasis Participants
NCT04316585 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluate Whether Combination Therapy With Methotrexate and Raptiva in Psoriasis Patients is Safe and Increases Efficacy
NCT00368654 ·Status: COMPLETED ·Phase: PHASE1/PHASE2