Mechanism Study of Ventilator-Induced Lung Injury in Elderly People.
NCT06367946 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2024-04-16
Summary
1. We collect lung tissues from patients with different ages and confirm that KLK8 expression is positively correlated with age.
2. We collect peripheral blood from patients with different ages and duration of mechanical ventilation to explore the correlation between the degree of endothelial/epithelial damage, age and duration of mechanical ventilation.
Conditions
- Ventilator-Induced Lung Injury
Interventions
- PROCEDURE
-
mechanical ventilation
Mechanical ventilation is machine-delivered flow of gases to both oxygenate and ventilate a patient who is unable to maintain physiological gas exchange.
Sponsors & Collaborators
-
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
lead OTHER
Principal Investigators
-
Lai Jiang, PhD · Department of Anesthesia, Shanghai Xinhua hospital, Shanghai China
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-06-01
- Primary Completion
- 2024-07-01
- Completion
- 2027-06-30
Countries
- China
Study Locations
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