Dexmedetomidine on Postoperative Cognitive Dysfunction and Serum Tau-217 Protein.
NCT06366412 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 94
Last updated 2024-04-15
Summary
To assess the effect of Dexmedetomidine on serum Tau-217 protein and its relation to the incidence and severity of postoperative cognitive dysfunction in elderly patients undergoing major surgery under general anesthesia.
Conditions
Interventions
- DRUG
-
Dexmedetomidine Hydrochloride
dexmedetomidine effect in preventing postoperative cognitive dysfunction on elderly patients undergoing major surgery guided with serum Tau-217 protein.
- OTHER
-
normal saline
normal saline will be administrated in placebo group
Sponsors & Collaborators
-
Minia University Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SCREENING
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-04-30
- Primary Completion
- 2025-03-31
- Completion
- 2026-03-31
Countries
- Egypt
Study Locations
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