Olezarsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency

NCT00743483 ·Status: COMPLETED ·Phase: PHASE2

A Cross-over Study of OligoG in Subjects With Cystic Fibrosis. Fibrosis

NCT01465529 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

NCT06747858 ·Status: RECRUITING ·Phase: PHASE2

A Study to Assess How Food Affects the Safety and Pharmacokinetics of Galicaftor and Navocaftor

NCT05538585 ·Status: COMPLETED ·Phase: PHASE1

A Phase 2b Randomised, Placebo Controlled Study of OligoG in Patients with Cystic Fibrosis

NCT03822455 ·Status: TERMINATED ·Phase: PHASE2

Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans

NCT01273207 ·Status: COMPLETED ·Phase: PHASE2

Dose Escalation Study of QR-010 in Homozygous ΔF508 Cystic Fibrosis Patients

NCT02532764 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)

NCT06526923 ·Status: RECRUITING ·Phase: PHASE1/PHASE2

Effect of Lumacaftor-ivacaftor on Glucose Handling and Tolerance in Cystic Fibrosis Phe508del

NCT02653027 ·Status: WITHDRAWN ·Phase: NA

Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation

NCT02589236 ·Status: COMPLETED ·Phase: PHASE2

A Study of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) in Healthy Adult Panelists

NCT06299696 ·Status: COMPLETED ·Phase: PHASE1

A Rollover Safety Study of Lumacaftor/Ivacaftor in Subjects Aged 2 Years and Older With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

NCT03125395 ·Status: COMPLETED ·Phase: PHASE3

Safety and Efficacy of Inhaled OligoG CF-5/20 for the Treatment Cystic Fibrosis

NCT00970346 ·Status: COMPLETED ·Phase: PHASE1

Study to Evaluate the Safety of CB-280 in Patients With Cystic Fibrosis

NCT04279769 ·Status: COMPLETED ·Phase: PHASE1

A Double-blind, Randomized, Multicenter, Cross-over Study to Compare the Effect of Creon N and Creon® on Fat Digestion in Subjects ≥ 12 Years of Age With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

NCT02137382 ·Status: COMPLETED ·Phase: PHASE3

A Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of IONIS-ENaCRx in Healthy Volunteers and Patients With Cystic Fibrosis

NCT03647228 ·Status: COMPLETED ·Phase: PHASE1

Pharmacokinetics of GLPG3067 in Male Subjects With Cystic Fibrosis.

NCT03589313 ·Status: COMPLETED ·Phase: PHASE1

Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency (PEI) Due to Cystic Fibrosis (CF)

NCT00690820 ·Status: COMPLETED ·Phase: PHASE3

A Study to Evaluate Safety and Pharmacokinetics of VX-659 in Healthy Subjects and in Adults With Cystic Fibrosis

NCT03029455 ·Status: COMPLETED ·Phase: PHASE1

An Efficacy and Safety Study of Ivacaftor in Patients With Cystic Fibrosis and Two Splicing Mutations

NCT02934698 ·Status: COMPLETED ·Phase: PHASE3

A Study to Evaluate Efficacy of Ivacaftor in Subjects With Cystic Fibrosis Who Have a 3849 + 10KB C→T or D1152H CFTR Mutation

NCT03068312 ·Status: COMPLETED ·Phase: PHASE3

Study of GLPG1837 in Subjects With Cystic Fibrosis (S1251N Mutation)

NCT02690519 ·Status: COMPLETED ·Phase: PHASE2

Tezacaftor/Ivacaftor Combination Therapy Expanded Access Program for Patients 12 Years of Age and Older With Cystic Fibrosis

NCT03278314 ·Status: APPROVED_FOR_MARKETING

Safety, Tolerability, and Pharmacokinetics of ARCT-032 in Healthy Adult Subjects and Adults With Cystic Fibrosis.

NCT05712538 ·Status: COMPLETED ·Phase: PHASE1

A Study To Evaluate the Relative Bioavailability, Food Effect, and Dose Proportionality of a Granule Formulation of Vanzacaftor/Tezacaftor/Deutivacaftor(VNZ/TEZ/D-IVA)

NCT06299709 ·Status: COMPLETED ·Phase: PHASE1