A Study of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) in Healthy Adult Panelists

Study of VX-121 in Healthy Subjects and in Subjects With Cystic Fibrosis

NCT03768089 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age

NCT03691779 ·Status: COMPLETED ·Phase: PHASE3

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of VX-661/Ivacaftor in Pediatric Subjects With Cystic Fibrosis (CF)

NCT02953314 ·Status: COMPLETED ·Phase: PHASE3

A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis

NCT03224351 ·Status: COMPLETED ·Phase: PHASE2

A Study Evaluating the Safety and Efficacy of VX-440 Combination Therapy in Subjects With Cystic Fibrosis

NCT02951182 ·Status: COMPLETED ·Phase: PHASE2

Evaluation of ELX/TEZ/IVA in Cystic Fibrosis (CF) Subjects 2 Through 5 Years

NCT04537793 ·Status: COMPLETED ·Phase: PHASE3

A Study Evaluating Safety and Pharmacokinetics of VX-440 in Combination With Tezacaftor/Ivacaftor in Healthy Adult Subjects

NCT03486236 ·Status: COMPLETED ·Phase: PHASE1

Pharmacokinetics and Safety Assessment of VX-121/Tezacaftor/Deutivacaftor in Participants With Moderate Hepatic Impairment

NCT05437120 ·Status: COMPLETED ·Phase: PHASE1

A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis

NCT03912233 ·Status: COMPLETED ·Phase: PHASE2

A Phase 1 Study to Evaluate the Relative Bioavailability of a VX-828 Tablet Formulation

NCT06861413 ·Status: COMPLETED ·Phase: PHASE1

A Study to Evaluate Safety, Efficacy, and Tolerability of TEZ/IVA in Orkambi® (Lumacaftor/Ivacaftor) -Experienced Subjects With Cystic Fibrosis (CF)

NCT03150719 ·Status: COMPLETED ·Phase: PHASE3

A Study to Assess the Effect of ELX/TEZ/IVA on Glucose Tolerance in Participants With Cystic Fibrosis (CF)

NCT04599465 ·Status: COMPLETED ·Phase: PHASE3

Taste Receptors Regulation in CF Patients

NCT04058340 ·Status: UNKNOWN ·Phase: NA

A Phase 2 Study to Evaluate Effects of VX-661/Ivacaftor on Lung and Extrapulmonary Systems in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

NCT02508207 ·Status: COMPLETED ·Phase: PHASE2

Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis

NCT06154447 ·Status: RECRUITING ·Phase: PHASE1

A Phase 2 Study to Evaluate Efficacy and Safety of VX-561 in Subjects Aged 18 Years and Older With Cystic Fibrosis

NCT03911713 ·Status: COMPLETED ·Phase: PHASE2

Pharmacokinetics of Vancomycin for Inhalation in Cystic Fibrosis

NCT01509339 ·Status: WITHDRAWN ·Phase: PHASE1

Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age

NCT05882357 ·Status: COMPLETED ·Phase: PHASE3

Study for Evaluating the Real Use of Inhaled Aztreonam Lysine in Patients With Cystic Fibrosis

NCT03607396 ·Status: UNKNOWN

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

NCT05444257 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

A Study Evaluating the Safety of VX-152 Combination Therapy in Adults With Cystic Fibrosis

NCT02951195 ·Status: COMPLETED ·Phase: PHASE2

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older

NCT05153317 ·Status: COMPLETED ·Phase: PHASE3

A Study Evaluating the Safety of Elexacaftor/Tezacaftor/Ivacaftor in Participants With Cystic Fibrosis (CF)

NCT05111145 ·Status: COMPLETED ·Phase: PHASE3

Pilot Study Testing the Effect of Ivacaftor on Lung Function in Subjects With Cystic Fibrosis and Residual CFTR Function

NCT01685801 ·Status: COMPLETED ·Phase: PHASE2

A Study Evaluating the Long Term Safety and Efficacy of VX-659 Combination Therapy

NCT03447262 ·Status: TERMINATED ·Phase: PHASE3