Dasatinib Combined With Quercetin to Reverse Chemo Resistance in Triple Negative Breast Cancer
NCT06355037 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2024-07-08
Summary
This is a Phase II, open-label, single-arm study evaluating the efficacy and safety of combined treatment of dasatinib, quercetin with chemotherapy in mTNBC (triple negative breast cancer) patients who progressed during previous chemotherapy.
Conditions
- Triple-negative Breast Cancer
Interventions
- DRUG
-
Quercetin
quercetin 1000mg d1-d3, qw
- DRUG
-
Dasatinib 50mg d1-d3, qw
- DRUG
-
Taxane/Anthracycline/Eribulin Mesylate/Vinorelbine/Capecitabine/Carboplatin/UTD1/platinum
Taxane/Anthracycline/Eribulin Mesylate/Vinorelbine/Capecitabine/Carboplatin/UTD1/platinum
Sponsors & Collaborators
-
Fudan University
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-05-20
- Primary Completion
- 2024-12-31
- Completion
- 2025-01-31
Countries
- China
Study Locations
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