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Sex Hormones and Inflammatory Biomarkers in Patients With Sickle Cell Disease

NCT06345638 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 52

Last updated 2025-08-05

No results posted yet for this study

Summary

This study aims to characterize sex differences in the pathophysiology of vaso-occlusive crises (VOC) occurring among individuals with sickle cell disease (SCD).

* The study will compare CRP and other biomarkers between females with SCD in the follicular phase of the menstrual cycle and males with SCD.
* The study will explore potential sex differences in biomarker changes between females and males with SCD during and following resolution of VOC.
* The study will compare neutrophil and platelet adhesion to the endothelium and real time fibrin deposition in the blood.

Conditions

Sponsors & Collaborators

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-03-01
Primary Completion
2025-06-17
Completion
2025-06-17

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06345638 on ClinicalTrials.gov