Anesthesia and Non-small Cell Lung Cancer Recurrence
NCT06330038 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 5384
Last updated 2026-04-20
Summary
There has been ongoing debate about the relationship between cancer recurrence and anesthetic management. Therefore, the investigators will test the hypothesis that the recurrence free survival (RFS) after curative resection of NSCLC is higher in patient who received total intravenous anesthesia (TIVA) than volatile anesthetics in this multi-center randomized trials.
Conditions
- Non-small Cell Lung Cancer
- Surgery
- Anesthesia
Interventions
- DRUG
-
Propofol
Propofol will be used for the induction and maintenance of general anesthesia.
- DRUG
-
Inhaled anesthetics
Inhaled anesthetics will be used for the maintenance of general anesthesia.
Sponsors & Collaborators
-
Seoul National University Hospital
collaborator OTHER -
Asan Medical Center
collaborator OTHER -
Severance Hospital
collaborator OTHER -
Seoul St. Mary's Hospital
collaborator OTHER -
Korea University Guro Hospital
collaborator OTHER -
DongGuk University
collaborator OTHER -
Inha University Hospital
collaborator OTHER -
Konkuk University Medical Center
collaborator OTHER -
Ewha Womans University
collaborator OTHER -
Chungnam National University Hospital
collaborator OTHER -
University of Virginia
collaborator OTHER -
Memorial Sloan Kettering Cancer Center
collaborator OTHER -
Yale University
collaborator OTHER - collaborator OTHER
-
University of Texas Southwestern Medical Center
collaborator OTHER -
University Hospitals Coventry and Warwickshire NHS Trust
collaborator OTHER -
Khon Kaen University
collaborator OTHER -
King Chulalongkorn Memorial Hospital
collaborator OTHER -
The Affiliated Hospital of Qingdao University
collaborator OTHER -
Beijing Hospital
collaborator OTHER_GOV -
All India Institute of Medical Sciences
collaborator OTHER -
Samsung Medical Center
lead OTHER
Principal Investigators
-
Hyun Joo Ahn · Department of Anesthesiology and Pain Medicine, Samsung Medical Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-08-05
- Primary Completion
- 2028-12-31
- Completion
- 2028-12-31
Countries
- South Korea
Study Locations
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