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Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome

NCT06325618 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2024-03-22

No results posted yet for this study

Summary

100 women with karyotype verified TS, previously examined at 4 study visits during a 19-year period will be asked to participate in a 5th study visit. Healthy age-matched females will be included as controls in a ratio 2:1.

The aim is to examine and quantify the cardiovascular and lymphatic system in women with TS. The investigators will study a possible causal mechanism between the known pathologic phenotype and alterations in these systems to understand, prevent or treat the life-threatening complications in TS.

Conditions

Interventions

OTHER

No intervention other than obtaining biopsies

Skin, fat, and muscle biopsies will be obtained

DRUG

Indocyanine green (ICG)

Indocyanine green will be injected to evaluate the lymphatic system.

Sponsors & Collaborators

  • Aarhus University Hospital

    collaborator OTHER

  • University of Aarhus

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-01-08
Primary Completion
2027-08-31
Completion
2027-08-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06325618 on ClinicalTrials.gov