Phase I/II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
NCT06308588 · Status: RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2026-05-15
Summary
To learn if the combination of blinatumomab and asciminib can help to control Ph+ ALL.
Conditions
- Philadelphia Chromosome-Positive
- Acute Lymphoblastic Leukemia
Interventions
- DRUG
-
Given by Infusion
- DRUG
-
Asciminib
Given by PO
Sponsors & Collaborators
- collaborator INDUSTRY
-
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Nicholas Short, MD · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-08-05
- Primary Completion
- 2027-05-01
- Completion
- 2029-05-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
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