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Prioritization of Cerebral Deoxygenation in Severe Traumatic Brain Injury and Mortality Benefit.

NCT06306950 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2024-03-15

No results posted yet for this study

Summary

Severe traumatic brain injury with a decrease in cerebral oximetry is associated with multiple impaired systemic microcirculations, more morbidities, and a higher mortality rate. When using the brain as an index organ, interventions to improve brain oxygen delivery may have systemic benefits for these patients.

Conditions

  • Cerebral Hypoxia
  • Severe Traumatic Brain Injury

Interventions

DEVICE

Near infrared spectroscopy neuromonitor to prevent cerebral desaturation

patients were assigned into active treatment (intervention) or usual care (control) groups with cerebral oximetry monitoring using NIRS bilaterally (Root; Prime Medical Corporation, MASIMO, USA) \[17\]. After cleansing the adjacent skin area with alcohol, an adhesive optode pad was placed over each frontal to temporal area. Resting baseline rSO2 values were obtained after waiting at least 1 minute after the placement of the sensors.

Sponsors & Collaborators

  • Phramongkutklao College of Medicine and Hospital

    lead OTHER

Principal Investigators

  • PANU BOONTOTERM, MD., FRCNST · Phramongkutklao College of Medicine and Hospital

  • Suthee Panichkul, MD. · Phramongkutklao College of Medicine and Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-04-01
Primary Completion
2024-02-28
Completion
2024-02-28

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06306950 on ClinicalTrials.gov