Neoadjuvant Chemoradiotherapy Followed by Sequential Immunotherapy for Thoracic Esophageal Squamous Cell Carcinoma
NCT06303583 · Status: ENROLLING_BY_INVITATION · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2024-03-12
Summary
The purpose of study is to investigate the safety and efficacy of sequential immunotherapy with neoadjuvant chemoradiotherapy for esophageal cancer
Conditions
Interventions
- DRUG
-
paclitaxel, 50 mg/m2, QW\*5
- DRUG
-
area under the curve of2mg/mL/min, QW\*5
- DRUG
-
tislelizumab
200mg Q3W, 2cycles
- RADIATION
-
radiotherapy
41.4Gy in 23 fractions
Sponsors & Collaborators
-
Qiu Guoqin
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-01
- Primary Completion
- 2024-08-31
- Completion
- 2026-12-31
Countries
- China
Study Locations
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