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Autonomic and Metabolic Response to Cardiac Rehabilitation After Acute MI

NCT06298513 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 25

Last updated 2025-08-21

No results posted yet for this study

Summary

Ischemic heart disease remains the leading cause of death in the western world. The beneficial effects of cardiac rehabilitation on the evolution of ischemic heart disease are known, but the effects of rehabilitation on the metabolic processes of the patients are so far poorly understood. Metabolomics is the qualitative/quantitative analysis of the body's metabolic responses to pathophysiological stimuli or genetic alterations. Metabolic changes caused by physical activity have been demonstrated in obese and diabetic patients and in athletes. Aim of the study is to evaluate whether cardiac rehabilitation after a first myocardial infarction induces changes in the metabolic state of patients, and whether these changes may be related with changes in the usual risk factors (i.e. glyco-lipidic profile, natriuretic peptides, homocysteine).

Conditions

  • Acute Myocardial Infarction: Rehabilitation Phase

Interventions

OTHER

Cardiac rehabilitation

Six weeks of cardiac rehabilitation with physical training

Sponsors & Collaborators

  • Istituto Auxologico Italiano

    lead OTHER

Eligibility

Min Age
25 Years
Max Age
75 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-02
Primary Completion
2024-06-12
Completion
2025-01-13

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06298513 on ClinicalTrials.gov