Early Variations in Immune Aging
NCT06295354 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2025-05-01
Summary
Background:
Despite an increase in lifespan over the last decades, our healthspan lags behind. In our aging population, it is pressing that we prevent age-related morbidities and associated burden on the health care system. Instead of investigating aging in already aged populations, the currently proposed study aims to elucidate the process of immune aging in relation to biological aging, demographic and lifestyle factors in young and midlife adults, and to identify early biomarkers and pathways associated with fast versus slow immune aging and aging endotypes.
Study design:
A single-center, observational prospective cohort study in the Netherlands. Participants from priorly established cohorts will be invited to join the EVIA-study. We will obtain demographic and basic clinical data and biological samples (blood and stool) at baseline and after three years, with a short, yearly online questionnaire in between.
Conditions
- Aging
- Aging Well
- Immuno Aging
Interventions
- OTHER
-
No intervention, we just study 'aging'
No intervention, we just study 'aging'
Sponsors & Collaborators
-
Radboud University Medical Center
lead OTHER
Eligibility
- Min Age
- 20 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-10-07
- Primary Completion
- 2025-01-27
- Completion
- 2025-03-18
Countries
- Netherlands
Study Locations
More Related Trials
-
Rheumatoid Arthritis Disease Activity Monitor
NCT00989677 ·Status: COMPLETED
-
Adalimumab in Rheumatoid Arthritis. An Investigation of Wholebody MRI, Conventional MRI, CT and Circulating Biomarkers
NCT01029613 ·Status: COMPLETED
-
Rheumatologists and the Requesting of Antinuclear Antibodies (ANA) Tests in Patients With Rheumatologic Complaints
NCT02409251 ·Status: COMPLETED ·Phase: NA
-
Detection of Pathological Lymphocytes in Patients With Autoimmune Disease
NCT02813083 ·Status: COMPLETED
-
Metabolome Analysis in Patients With Rheumatoid Arthritis
NCT02960958 ·Status: UNKNOWN
-
Immunophenotyping From Blood of Patients Suffering From Chronic Degenerating Joint Diseases and Receiving LDRT
NCT02653079 ·Status: RECRUITING
-
Health Outcomes in Rheumatoid Arthritis
NCT00346411 ·Status: COMPLETED
-
STudying Ageing in Rheumatic Diseases (STAR)
NCT05463666 ·Status: ACTIVE_NOT_RECRUITING
-
High Intensity Interval Training and Rheumatoid Arthritis
NCT02528344 ·Status: COMPLETED ·Phase: NA
-
Characterization of Immunogenicity of TNF Inhibitors in Arthritis Patients With Poorer Treatment Response.
NCT04731831 ·Status: RECRUITING
-
An MRI-guided Treatment Strategy to Prevent Disease Progression in Patients With Rheumatoid Arthritis
NCT01656278 ·Status: COMPLETED ·Phase: NA
-
Remote Care in People With Rheumatoid Arthritis
NCT05496855 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Impact of Air Pollution on the Course of Inflammatory Rheumatism
NCT05862584 ·Status: COMPLETED ·Phase: NA
-
Chronic Pain in Rheumatoid Arthritis
NCT05038553 ·Status: RECRUITING
-
RETRO (REduction of Therapy in RA Patients in Ongoing Remission)
NCT02779114 ·Status: UNKNOWN ·Phase: PHASE3
-
Oral Metagenomic Biomarkers in Rheumatoid Arthritis
NCT02544334 ·Status: COMPLETED
-
Medication Adherence in Rheumatic Diseases
NCT06018350 ·Status: COMPLETED ·Phase: NA
-
Prospective Study of Patients With Rheumatoid Arthritis After the Age of 65
NCT02686320 ·Status: TERMINATED
-
Long-term Observation of Patients With Early Rheumatoid Arthritis
NCT00240136 ·Status: COMPLETED
-
Interstitial Lung Disease in Early Rheumatoid Arthritis
NCT03977415 ·Status: UNKNOWN
-
Characterization of the Phenotypic Markers of B Cell Lymphocytes in Rheumatoid Arthritis
NCT03793270 ·Status: UNKNOWN
-
Feasibility of a Cytokine Expression Profile in Immune Cells as an Orientation Tool in Therapeutic Decisions for Auto-inflammatory and Auto-immune Diseases
NCT03280797 ·Status: COMPLETED ·Phase: NA
-
Evaluation by HR-pQCT of Bone Microarchitecture Changes in Patients With Rheumatoid Arthritis Under Anti-TNF Therapy.
NCT02526992 ·Status: TERMINATED ·Phase: NA
-
Reducing Sedentary Time in Rheumatoid Arthritis: The Take a STAND for Health Study
NCT03186924 ·Status: UNKNOWN ·Phase: NA
-
Discovering the Antecedents of Rheumatoid Arthritis Flare
NCT02051114 ·Status: ACTIVE_NOT_RECRUITING