Relation Between Tumor-draining Lymph Nodes Metastasis Pattern and Non-small Cell Lung Cancer Neoadjuvant Immunotherapy Effectiveness
NCT06292052 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 209
Last updated 2024-05-14
Summary
The goal of this retrospective cohort analysis is to discover the impact of the involvement extent of tumor-draining lymph nodes (TDLNs) in patients who received neoadjuvant immunochemotherapy. The main question it aims to answer is the role of TDLN in the prediction of treatment effectiveness. Researches will compare tumor-draining lymph nodes metastasis (mTDLNs) group and non-draining lymph nodes metastasis (mNDLNs) group to see whether different metastatic patterns of mediastinal lymph nodes can indicate the treatment effectiveness.
Conditions
Interventions
- DRUG
-
Immunotherapy
Received neoadjuvant chemotherapy plus immunotherapy
Sponsors & Collaborators
-
Jiangmen Central Hospital
collaborator OTHER -
Henan Cancer Hospital
collaborator OTHER_GOV -
Sun Yat-sen University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-01
- Primary Completion
- 2024-03-01
- Completion
- 2024-04-01
Countries
- China
Study Locations
More Related Trials
-
Study of Changes of Lymphocyte Subsets in Chemotherapy Course of Patients With Non-small Cell Lung Cancer
NCT02202655 ·Status: UNKNOWN
-
The Predictive Biomarkers in Patients With Locally Advanced Non-small Cell Lung Cancer
NCT06287320 ·Status: RECRUITING
-
Survival Analysis and Prognostic Biomarker Exploration of Postoperative Adjuvant Therapy Patterns in Patients With Non-small Cell Lung Cancer After Neoadjuvant Immunotherapy
NCT07256002 ·Status: ACTIVE_NOT_RECRUITING
-
Neoadjuvant Immunochemotherapy for Lung Cancer
NCT06023797 ·Status: COMPLETED
-
Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) Scan
NCT06358222 ·Status: RECRUITING
-
An Observational Study to Explore Clinical Characteristics of the Patients With T1 Non-small Cell Lung Cancer
NCT03413956 ·Status: COMPLETED
-
Artificial Intelligence-based Model for the Prediction of Occult Lymph Node Metastasis and Improvement of Clinical Decision-making in Non-small Cell Lung Cancer
NCT06684418 ·Status: RECRUITING
-
Analysis of Driver Gene Mutation in Early Stage Non-small Cell Lung Cancer
NCT04266691 ·Status: COMPLETED
-
Lobectomy-First vs. Lymphadenectomy-First for Operable NSCLC (LOFTY)
NCT06577792 ·Status: RECRUITING ·Phase: NA
-
Safety and Efficiency of γδ T Cell Against Lung Cancer
NCT03183232 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety, Efficacy, and Survival Outcomes of Neoadjuvant/Induction Immunotherapy in Surgical and Radiotherapeutic Management of Non-Small Cell Lung Cancer
NCT06926179 ·Status: RECRUITING
-
Real-Time Image Guided Lymphatic Mapping and Nodal Targeting in Lung Cancer
NCT00264602 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Integrative Multi-Omics Testing for Immunotherapy Response in Non-Small Cell Lung Cancer
NCT05928299 ·Status: COMPLETED
-
Deep Learning Model for Pure Solid Nodules Classification
NCT05542992 ·Status: UNKNOWN
-
Clinical Study on the Prevention of Driver Gene Negative Ib-IIIb Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors
NCT05834413 ·Status: RECRUITING ·Phase: NA
-
Efficacy of Neoadjuvant Immunotherapy in Patients With Lung Cancer
NCT07166003 ·Status: RECRUITING
-
Retrospective Comparative Study of Routine Lower Neck CT in the Staging and Diagnosis of Lung Cancer Across Two Cohorts
NCT03522090 ·Status: UNKNOWN
-
Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens
NCT06252129 ·Status: RECRUITING ·Phase: NA
-
Prognostic Significance of the Uncertain Resection in NSCLC
NCT06511661 ·Status: ACTIVE_NOT_RECRUITING
-
Local and Peripheral Immune Responsive Landscape Induced by Local Cryoablation in Patients With Lung Adenocarcinoma
NCT06104709 ·Status: NOT_YET_RECRUITING
-
A Study of the Correlation Between CRF, Survival and Physiological Factors in NSCLC Patients Under Chemotherapy
NCT03130192 ·Status: UNKNOWN
-
The Establishment and Clinical Application of a Prediction Model of Lung Cancer Distant Metastasis Based on the Genomic Characteristics of Circulating Tumor Cells
NCT04568720 ·Status: UNKNOWN
-
A Study to Explore Clinical Characteristics and Prognoses of N2 Patients With Non-small Cell Lung Cancer
NCT03429192 ·Status: COMPLETED
-
Predictive Gene Profiles and Dynamic Measurement of Treatment Response in Metastatic Non-small Cell Lung Cancer
NCT03512847 ·Status: COMPLETED
-
Immune Treatment of Brain Metastasis of Lung Cancer Combined With Large-segmentation Precision Radiotherapy
NCT05584267 ·Status: RECRUITING ·Phase: PHASE2