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Removal Of CytoKines With cytoSorbenTs After Inflammatory Response Reaction During Cardiac Surgery

NCT06286280 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2025-04-06

No results posted yet for this study

Summary

Detailed knowledge about the association between systemic inflammation and endothelial progenitor cell (EPCs) activation during extracorporeal circulation (ECC) is lacking.

This pilot study aims to clarify the relationship between CD34-positive EPCs and cytokine release during ECC using the cytokine adsorber to make a predictive statement regarding the clinical expression of inflammation.

Conditions

  • Inflammatory Response

Interventions

DEVICE

cytokine adsorber (CytoSorb®)

binding of cytokines to the sorbent polystyrene of the adsorber during cardiac surgery with extracorporeal circulation

Sponsors & Collaborators

  • Deutsche Stiftung für Herzforschung

    collaborator OTHER

  • University of Giessen

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-01
Primary Completion
2024-12-01
Completion
2025-03-27

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06286280 on ClinicalTrials.gov