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Metagenomic Analysis of Gut Microbiota in Untreated and Uncontrolled Hypertensive Patients

NCT06284928 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 192

Last updated 2026-01-02

No results posted yet for this study

Summary

This observational study aims to explore the relationship between gut microbiota composition and blood pressure regulation in patients with hypertension. A total of 192 participants will be enrolled, including newly diagnosed untreated hypertensive patients, patients with uncontrolled hypertension under medication, and healthy controls. Fecal samples will be collected for metagenomic sequencing to identify microbial taxa and functional pathways associated with blood pressure levels. The findings are expected to reveal characteristic microbial patterns linked to hypertension and provide potential microbial targets for improving antihypertensive therapy.

Conditions

Interventions

OTHER

Fecal Sample Collection

Non-invasive stool sample collection for gut microbiota metagenomic analysis. No drug or behavioral intervention involved.

Sponsors & Collaborators

  • Xinjiang Medical University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-12-01
Primary Completion
2020-06-01
Completion
2020-12-01

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06284928 on ClinicalTrials.gov