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Risk Factors for Neuroendocrine Neoplasms

NCT06282016 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 14250

Last updated 2026-01-07

No results posted yet for this study

Summary

Recent studies show an increase in neuroendocrine neoplasms, especially for the digestive tract. Previous studies suggest various risk factors that were observed for various tumor sites, e.g. a family history of cancer, tobacco and alcohol consumption as well as metabolic disorders including diabetes and obesity. A risk factor that has been little studied to date is depressive disorders, which could increase the risk of neuroendocrine neoplasms either independently or through associated risk behaviors and/or antidepressant medication. The aim of this study is to identify risk factors for neuroendocrine neoplasms based on a case-control study in order to better understand the increase of neuroendocrine neoplasms in recent decades. The study is based on a record linkage of data from the Bavarian Cancer Registry and data from the Bavarian Association of Statutory Health Insurance Accredited Physicians. While the data from the Bavarian Cancer Registry enables the identification of neuroendocrine neoplasms on the basis of histopathological findings and thus is the basis for selecting cases, the claims data from the Bavarian Association of Statutory Health Insurance Accredited Physicians provides the source population as well data on diagnoses and thus enables the investigation of risk factors.

Conditions

  • Neuroendocrine Neoplasm of Lung
  • Neuroendocrine Neoplasm of Gastrointestinal Tract (Disorder)

Interventions

OTHER

Case-control study (no intervention)

Observation of risk factors in cases and controls

Sponsors & Collaborators

  • Bavarian Association of Statutory Health Insurance Accredited Physicians

    collaborator UNKNOWN

  • Bavarian Cancer Registry

    lead OTHER_GOV

Principal Investigators

  • Jacqueline Müller-Nordhorn · Bavarian Cancer Registry, Bavarian Health and Food Safety Authority

  • Martin Tauscher · Bavarian Association of Statutory Health Insurance Accredited Physicians

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-15
Primary Completion
2026-02-28
Completion
2026-08-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06282016 on ClinicalTrials.gov