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The Effect of Late-evening Snacks on Patients With Primary Hepatocellular Carcinoma After Hepatectomy

NCT06278701 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 106

Last updated 2024-02-26

No results posted yet for this study

Summary

Late-evening snacks, in which a portion of food is moved to bedtime while the total amount of food eaten per day remains unchanged, can effectively improve the metabolic state of accelerated catabolism.

The goal of this clinical trial is to learn about the effects of late-evening snacks on health conditions of hepatocellular carcinoma patients who underwent hepatectomy, and to further explore the effects of late-evening snacks on patients' metabolic patterns. The main question it aims to answer are: • the effect of late-evening snacks on the nutritional status of hepatic resection patients with hepatocellular carcinoma;

* the effect of late-evening snacks on the recovery of liver function in liver cancer hepatectomy patients;
* the effect of late-evening snacks on the complication rate of hepatic resection patients with hepatocellular carcinoma;
* the effect of late-evening snacks on long-term quality of life of hepatic resection patients with hepatocellular carcinoma;
* the effect of late-evening snacks on the metabolic pattern of hepatic resection patients with hepatocellular carcinoma.

After learning about the 2 dietary modalities of the late-evening snacks and regular diet, patients will be placed in the different groups according to your preference. Patients who enter the test group will have additional meal 1h before bedtime every day, while patients in the control group will have normal diet. Patients will be asked to :

* eat 1h before bedtime;
* follow the doctor's instructions during their stay in the hospital;
* have follow-up examinations at 1 month, 3 months and 6 months after the operation, after which blood samples will be collected for metabolite testing.

Conditions

  • Liver Neoplasms

Interventions

OTHER

late-evening snacks

have an additional meal 1h before bedtime (total calories 200-275kcal, protein 11.5g-18g, complex carbohydrates 25-55g).

Sponsors & Collaborators

  • DU Yao

    lead OTHER

Principal Investigators

  • Yao Du, Master · Drum Tower Hospital, Medical School of Nanjing University

Study Design

Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-11-01
Primary Completion
2025-01-31
Completion
2025-07-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06278701 on ClinicalTrials.gov