Early Diagnosis of Gastric Cancer Cachexia
NCT06277986 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2024-02-26
Summary
Gastric cancer is one of the most common malignancies, the morbidity and mortality of which are among the highest. In cancer patients, the incidence of cachexia is very high, and even 80% of patients will eventually develop into cachexia. However, once gastric cancer patients develop cachexia, patients are unlikely to obtain clinically significant benefits from conventional treatment. Therefore, it is important to find biomarkers for early detection of cachexia. The investigators carried out a plasma-derived exosomal microRNA(miRNA) study for early diagnosis of cachexia in gastric cancer, and the development of early diagnosis kits for gastric cancer cachexia.
Conditions
- Cachexia
Interventions
- OTHER
-
cachexia
Cachexia mainly manifests as weight loss. 1)weight loss \>5% over past 6 months. 2)BMI\<20 and any degree of weight loss \>2%. 3)Appendicular skeletal muscle index consistent with sarcopenia and any degree of weight loss \>2%.
Sponsors & Collaborators
-
Xijing Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-06-01
- Primary Completion
- 2024-09-01
- Completion
- 2024-09-01
Countries
- China
Study Locations
More Related Trials
-
Optimizing the Strategy for Preoperative Chemotherapy in Locally Advanced Gastric/Gastroesophageal Cancer
NCT02725424 ·Status: COMPLETED ·Phase: PHASE2
-
Integrative Analysis of Exosome-Mediated Single-Cell Transcriptomics and Proteomics in Gastric Cardia Cancer
NCT06702891 ·Status: RECRUITING
-
Appraisal of the Modified Cancer Cachexia Index in Locally Advanced Gastric Cancer Patients Undergoing Neoadjuvant Chemotherapy
NCT06689462 ·Status: COMPLETED
-
Gastric Cancer Organoids in the Screening of Neoadjuvant Drugs
NCT06196554 ·Status: RECRUITING
-
Tumor Microenvironment in Gastric Cancer Patients Treated With Combined Immunotherapy and Chemotherapy
NCT06202781 ·Status: RECRUITING
-
A Clinical Study of Docetaxel for Injection (Albumin-bound) in Patients With Gastric Cancer
NCT06296706 ·Status: RECRUITING ·Phase: PHASE3
-
Cabozantinib in High Grade Neuroendocrine Neoplasms
NCT04412629 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Immune Checkpoint Inhibitors (ICIs) Retreatment in Second-line Treatment of Advanced Gastric Cancer: a Retrospective, Real-world Study
NCT06814548 ·Status: NOT_YET_RECRUITING
-
Cisplatin,Docetaxel and S-1 for Advanced Gastric and Gastroesophageal Junction Cancer
NCT01747707 ·Status: UNKNOWN ·Phase: PHASE2
-
Prognostic and Predictive Impact of Circulating Tumor DNA in Gastric Cancer Treatment
NCT02674373 ·Status: UNKNOWN
-
Neoadjuvant Chemotherapy With SEEOX Regimen for Borrmann Type 4 Gastric Cancer
NCT02949258 ·Status: UNKNOWN ·Phase: PHASE2
-
The Efficacy of Precision Treatment for Gastric Cancer Guided by Molecular Profiling
NCT04501887 ·Status: UNKNOWN
-
Clinical Study of Irinotecan Liposome Combination Therapy for Advanced Gastric Cancer
NCT06499610 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Machine Learning-driven Noninvasive Screening of Transcriptomics Liquid Biopsies for Early Diagnosis of Occult Peritoneal Metastases in Locally Advanced Gastric Cancer
NCT06478394 ·Status: RECRUITING
-
Prediction of Neoadjuvant Chemotherapy Efficacy in Locally Advanced Gastric Cancer
NCT05140746 ·Status: RECRUITING ·Phase: NA
-
Predicting Biomarker of Gastric Cancer Chemotherapy Response
NCT03253107 ·Status: RECRUITING
-
Compare S-1 for 6 Months to 1 Year as Adjuvant Chemotherapy After D2 Resection in Patients With Gastric Cancer Staged II , IIIA or IIIB.
NCT02736552 ·Status: WITHDRAWN ·Phase: PHASE3
-
Study of S1 Efficacy and Toxicity as Second-line Treatment on Inoperable or Advanced Gastric Cancers
NCT01650766 ·Status: UNKNOWN
-
A Study on the Potential Benefit of Neoadjuvant Therapy for AGC Patients
NCT05442138 ·Status: UNKNOWN
-
Comparison of the Efficiency Between Intraoperative and Postoperative Hyperthermic Intraperitoneal Chemotherapy With Docetaxel Combine Oxaliplatin in Patients With Advanced Gastric Cancer
NCT04522011 ·Status: UNKNOWN
-
A Study to Evaluate Nivolumab in Patients With Unresectable Advanced/Metastatic Gastric Cancer and Gastroesophageal Junction Cancer
NCT06452329 ·Status: COMPLETED
-
Neo-Sequence 1: Neoadjuvant Chemotherapy With or Without Antiangiogenesis and Sequential Immunotherapy for HER2-negative MMR-proficient Locally Advanced Gastric or Gastroesophageal Adenocarcinoma
NCT05540145 ·Status: COMPLETED
-
A Multifactor Prediction Model for Non-curative Outcomes in Mixed-type Early Gastric Cancer
NCT07096947 ·Status: COMPLETED
-
The Efficacy and Safety of HIPEC Combined With PD-1 and SOX Chemotherapy for the Translational Treatment of GC or EGJC With PM
NCT06427252 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Explore the Efficacy and Safety of Atezolizumab Plus Tiragolumab and Chemotherapy in 1st Line HER2 Negative Unresectable, Recurrent or Metastatic Gastric Cancer or Adenocarcinoma of Gastroesophageal Junction (GEJ)
NCT04933227 ·Status: TERMINATED ·Phase: PHASE2