Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix)
NCT06266338 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2026-05-06
Summary
The main purpose of this study is to gather information about an investigational drug combination, Lenvatinib in combination with pembrolizumab, that may help to treat cervical cancers. In this study, we are looking to see whether the combination of lenvatinib and pembrolizumab has any effect on slowing tumor growth in cervical cancer tumors.
Conditions
- Cervix Cancer
- Cervical Cancer
Interventions
- DRUG
-
200 mg IV q 3 weeks
- DRUG
-
20 mg PO daily
Sponsors & Collaborators
- collaborator INDUSTRY
-
University of Texas Southwestern Medical Center
lead OTHER
Principal Investigators
-
Jayanthi Lea, MD · Professor and Division Chief, Obstetrics & Gynecology, OB-Gynecologic Oncology
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-03-11
- Primary Completion
- 2026-10-31
- Completion
- 2027-10-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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